Fei WANG ^*,a,b, Fu-Cai REN ^b, Ya-Ju Li ^b, and Ji-Kai LIU ^*,a

^a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Kunming 650204, China

^b BioBioPha Co., Ltd.; Kunming 650204, China

Abstract

Four new neo-clerodane diterpenoids, scutebarbatines W–Z (1–4), were isolated from the ethanol extract of Scutellaria barbata (Labiatae), and their structures were elucidated on the basis of extensive spectroscopic studies. In addition, the proposed structures of at least seven 13-spiro subtype neo-clerodanes: scutehenanine B (5), scutebarbatine G (6), 6-O-nicotinoylscutebarbatine G (7), barbatin A (8), 6,7-di-O-nicotinoylscutebarbatine G (9), 6-O-nicotinoyl-7-O-acetylscutebarbatine G (10), and scutebarbatine F (11), reported by Dai and co-workers from the same species, were incorrectly assigned and have been revised by reanalysis of the published NMR data.

文章链接：https://www.jstage.jst.go.jp/article/cpb/58/9/58_9_1267/_article/-char/ja/