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Prenylated Coumarins from Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata, Nat. Prod. Bioprospect., 2016, 6: 233–237.
发布时间:2019-08-02 阅读数:228 来源:原创
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Xiang-Mei Li . Xian-Jun Jiang . Ku Yang . Li-Xia Wang . Shi-Zhen Wen . Fei Wang


Received: 3 September 2016 / Accepted: 8 September 2016 / Published online: 19 September 2016

© The Author(s) 2016. This article is published with open access at Springerlink.com


Abstract

Four hitherto unknown prenylated coumarins, namely 6’’-O-β-D-apiofuranosylapterin (1), 4’-O-isobutyroylpeguangxienin (2), 6-(3-methyl-2-oxobutyroyl)-7-methoxycoumarin (3), and 6-hydroxycoumurrayin (4), were isolated from the ethanol extract of Heracleum stenopterum, Peucedanum praeruptorum, Clausena lansium, and Murraya paniculata, respectively. Their chemical structures were established on the basis of extensive spectroscopic analysis. Compound 2 exhibited in vitro cytotoxic activity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480) with IC50 values ranging from 15.9 to 23.2 μM.




文章链接:https://link.springer.xilesou.top/article/10.1007/s13659-016-0107-5




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