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Hybrid Monoterpenoid Indole Alkaloids Obtained as Artifacts from Rauvolfia tetraphylla, Nat. Prod. Bioprospect., 2015, 5: 247–253.
发布时间:2019-08-02 阅读数:201 来源:原创
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Yuan Gao . Dong-Sheng Zhou . Ping Hai . Yan Li . Fei Wang


Received: 2 September 2015 / Accepted: 24 September 2015 / Published online: 29 September 2015

© The Author(s) 2015. This article is published with open access at Springerlink.com


Abstract

Five new hybrid monoterpenoid indole alkaloids bearing an unusual 2,2-dimethyl-4-oxopiperidin-6-yl moiety, namely rauvotetraphyllines F–H (1, 3, 4), 17-epi-rauvotetraphylline F (2) and 21-epi-rauvotetraphylline H (5), were isolated from the aerial parts of Rauvolfia tetraphylla. Their structures were established by extensive spectroscopic analysis. The new alkaloids were evaluated for their cytotoxicity in vitro against five human cancer cell lines.



文章链接:https://link.springer.xilesou.top/article/10.1007/s13659-015-0074-2


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